John Stamos, who played the role of Uncle Jesse on the hit sitcom Full House, recently revealed while appearing on the Good Guys podcast that working alongside Mary-Kate Olsen and Ashley Olsen during the early days of the sitcom had its challenges. The twins were cast in the role of Michelle Tanner when they were less than a year old. The actor shared that he was responsible for briefly getting twins Ashley and Mary-Kate Olsen fired from the show. "I did it. I didn't try, I did it," Stamos said. "She was screaming—both of them. They wanted to be anywhere else but there, and so did I. They were 11 months old, and God bless them…but I couldn't deal with it. I said, ‘This is not gonna work, guys. Get rid of them. I can't work like this.'" John Stamos said that he requested that Ashly and Mary-Kate Olsen be brought back on set FULL HOUSE, John Stamos, Mary-Kate/Ashley Olsen, 1987-1995. © ABC /Courtesy Everett Collection The 59-year-old revealed that after firing the Olsen twins, the producers hired two read-headed children as replacements for them. However, Stamos admitted that the substitute could not match the twins' talent as they were truly one of a kind, and thus the Olsen Sisters were brought back to the show. RELATED: John Stamos Says “Shut Up” To “Full House” Theme Song "I said, 'Bring the Olsens back, these kids are terrible!'" he said. "It was a day or something, we tried the other kids, it didn't work." FULL HOUSE, clockwise from left: Ashley/Mary-Kate Olsen, Dave Coulier, Candace Cameron, John Stamos, Jodie Sweetin, Bob Saget, 1987-95. photo: Mario Casilli/TV Guide/courtesy Everett Collection John Stamos had issues with other members of the 'Full House cast The Olsen twins were not the only Full House Cast members that Stamos had difficulty getting along with initially on set. The actor previously confessed while attending the Cool Comedy, Hot Cuisine annual fundraiser for the Scleroderma Research Foundation in September 2022 that, at first, he didn't have the easiest time working with the late Bob Saget either. "The interesting thing was we didn't really like each other in the beginning," Stamos recalled "We were very different, we came from different approaches to acting, and slowly our differences made us interesting to each other." FULL HOUSE, (top, from left): John Stamos, Dave Coulier, (middle): Bob Saget, Candace Cameron, (bottom): Jodie Sweetin, Ashley Olsen, (1988), 1987-95. © Lorimar Televison / Courtesy: Everett Collection. Stamos further claimed that he and Saget were able to learn more about each other during the eight-season run of Full House and improve their working relationship. "And then we were best friends until the day he died," he said. "We were there for everything with each other: the good times, the bad times, divorces, marriages, kids. I don't know how I'm gonna get through the rest of this world without him."