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Celebrity News

Christina Applegate Thinks She Contracted COVID After Recent ‘Married With Children’ Reunion

by Ruth A

Published February 11, 2026

christina applegate covid

Christina Applegate is opening up about a recent health scare following a reunion with her Married… With Children co-stars. The actress, who has remained candid about her life since her multiple sclerosis diagnosis, now believes she may have contracted COVID-19 during the nostalgic event held in Los Angeles.

According to Yahoo! News, Christina Applegate shared on her Messy podcast that she is “certain” she picked up the virus at the Wiltern Theatre reunion. The evening brought together Ed O’Neill, Katey Sagal, and David Faustino before a crowd of thousands—a celebration that left Applegate both grateful and physically drained.

Related:

  1. Christina Applegate Leads ‘Married… With Children’ Reunion – And For A Good Cause
  2. Christina Applegate From ‘Married… With Children’ Is Now 51 And Battling MS

Christina Applegate Reflects On The Reunion Night

early signs of MS
Christina Applegate/Instagram

The event, titled “An Evening with the Bundys,” drew a couple thousand fans eager to see the cast together again. Applegate admitted she did not wear a mask and described the atmosphere as filled with “so many germs.” Though she tried to keep things light and funny during the moderated discussion, she now suspects that decision may have led to her illness.

Christina Applegate pain from MS
Christina Applegate/ImageCollect

Despite the health concerns that followed, Applegate said she enjoyed reconnecting with her television family. The night, however, proved exhausting. Because of her MS diagnosis in 2021, late evenings can take a toll. She explained that a 7:30 p.m. start time already felt overwhelming, joking that she would normally be in pajamas rather than in full hair and makeup before thousands of people.

Christina Applegate Shares Ongoing Health Struggles

MARRIED…WITH CHILDREN, Christina Applegate, (ca. early 1990s), 1987-1997. ph: Aaron Rapoport / TM and ©Fox Network. All rights reserved. / Courtesy Everett Collection

Applegate has spoken openly about how multiple sclerosis affects her daily life. She revealed that fatigue often hits hard, especially during long public appearances. Even so, she pushed through the reunion because of the joy it brought both her and longtime fans of the show.

MARRIED...WITH CHILDREN, (aka MARRIED WITH CHILDREN), clockwise from bottom left: Lucky (the Dog), David Faustino, Amanda Bearse, Katey Sagal, Christina Applegate, Ted McGinley, Ed O'Neill
MARRIED…WITH CHILDREN (aka MARRIED WITH CHILDREN), clockwise from bottom left: Lucky (the dog), David Faustino, Amanda Bearse, Katey Sagal, Christina Applegate, Ted McGinley, and Ed O’Neill (1996), 1987-1997. Ph: Larry Watson / TM and © Fox Network. All rights reserved / courtesy Everett Collection

The Dead to Me star has also reflected on how illness has reshaped her sense of self. In a previous podcast appearance, Christina Applegate admitted she misses the person she was before getting sick. She shared a particularly emotional moment when her daughter told her she missed who her mother used to be—a comment Applegate described as “like a knife to the heart.” Through it all, Applegate continues to show resilience, balancing honesty about her struggles with gratitude for the people who keep her going.

Next up: ‘90210’ Star Tori Spelling Facing Sad New Reality As Home Turns ‘Borderline Hoarder’ After Split
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